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Dr Ari Ercole

Dr Ari Ercole is a Fellow in Clinical Medicine and Director of Studies in Medical Science at Magdalene and affiliated associate professor in the Department of Medicine.

In addition to his role at Magdalene, Dr Ercole is a consultant in neurosciences and trauma intensive care and interim Chief Clinical Information Officer at Cambridge University Hospitals NHS Foundation Trust (CUHFT). His clinical interests focus on the physiological measurement, support and resuscitation of critically ill patients, in particular patients that have sustained life threatening severe trauma and in the use of digital technologies including artificial intelligence to improve the way healthcare is delivered.

Prior to his medical training, he completed a degree and PhD in condensed matter physics from the University of Cambridge.

Research Interests

Dr Ercole has an extensive background in physical and statistical modelling as well as data science and computing. His research involves development of novel medical technology (in particular data analysis techniques but also sensor development and physiological measurement) and its application to the treatment of critically ill patients in particular. He is interested in physiological signal complexity (fractal dynamics, signal entropy) as an emergent behaviour of networks of non-linear dynamical systems or techniques from machine learning and time-series statistics to neurophysiological and clinical data to detect and characterise novel multidimensional interrelationships.

Qualifications

  • BA
  • MB
  • BChir
  • MA (Cantab)
  • PhD

Professional Affiliations

  • Fellow of the Royal College of Anaesthetists
  • Fellow of the Faculty of Intensive Care Medicine
  • Fellow of the British Computer Society

Key Publications

TILTomorrow today: dynamic factors predicting changes in intracranial pressure treatment intensity after traumatic brain injury. Bhattacharyay S, van Leeuwen FD, Beqiri E, Åkerlund CAI, Wilson L, Steyerberg, EW, Nelson, DW, Maas AIR Menon DK, Ercole, A. Scientific Reports (2025), 15: 95.
http://doi.org/10.1038/s41598-024-83862-x

Clinical descriptors of disease trajectories in patients with traumatic brain injury in the intensive care unit (CENTER-TBI): a multicentre observational cohort study. Åkerlund CAI, Holst A, Bhattacharyay S, StocchettiN, Steyerberg E, Smielewski P, Menon DK, Ercole A, Nelson DW. The Lancet Neurology. (2023), 23: 71-80.
http://doi.org/10.1016/s1474-4422(23)00358-7

The leap to ordinal: Detailed functional prognosis after traumatic brain injury with a flexible modelling approach. Bhattacharyay, Shubhayu; Milosevic, Ioan; Wilson, Lindsay; Menon, David K.; Stevens, Robert D.; Steyerberg, Ewout W.; Nelson, David W.; Ercole, Ari. PLOS ONE. (2022), 17: 7
https://doi.org/10.1371/journal.pone.0270973